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tgfβ signaling phospho-specific antibody microarray  (Full Moon BioSystems)

 
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    Full Moon BioSystems tgfβ signaling phospho-specific antibody microarray
    Altered <t>TGFβ</t> signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.
    Tgfβ Signaling Phospho Specific Antibody Microarray, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tgfβ signaling phospho-specific antibody microarray/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    tgfβ signaling phospho-specific antibody microarray - by Bioz Stars, 2026-03
    90/100 stars

    Images

    1) Product Images from "Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects * ♦ "

    Article Title: Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects * ♦

    Journal: The Journal of Biological Chemistry

    doi: 10.1074/jbc.M113.493551

    Altered TGFβ signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.
    Figure Legend Snippet: Altered TGFβ signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.

    Techniques Used: Western Blot, Control

    Ectopic activation of noncanonical TGFβ signaling is prevented by reduction of TβRI/ALK5 in Tgfbr2fl/fl;Wnt1-Cre mice. A and B, immunoblotting analysis of ABL1, phosphorylated (P) ABL1, and tenascin C in tongues from E14.5 control (lane 1), Tgfbr2fl/fl;Wnt1-Cre (lane 2), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (lane 3) mice. C, quantitative RT-PCR analyses of tenascin C (TnC) in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001. D, Gomori's aldehyde fuchsin staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Purple, elastic fibers; green, collagen fibers and nuclei; red, muscle. Scale bar, 500 μm. E, AZAN staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Blue, collagen fibers; red, muscle; orange, nuclei. Bar, 500 μm. F, quantitative RT-PCR analyses of the indicated molecules in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001, *, p < 0.05.
    Figure Legend Snippet: Ectopic activation of noncanonical TGFβ signaling is prevented by reduction of TβRI/ALK5 in Tgfbr2fl/fl;Wnt1-Cre mice. A and B, immunoblotting analysis of ABL1, phosphorylated (P) ABL1, and tenascin C in tongues from E14.5 control (lane 1), Tgfbr2fl/fl;Wnt1-Cre (lane 2), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (lane 3) mice. C, quantitative RT-PCR analyses of tenascin C (TnC) in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001. D, Gomori's aldehyde fuchsin staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Purple, elastic fibers; green, collagen fibers and nuclei; red, muscle. Scale bar, 500 μm. E, AZAN staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Blue, collagen fibers; red, muscle; orange, nuclei. Bar, 500 μm. F, quantitative RT-PCR analyses of the indicated molecules in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001, *, p < 0.05.

    Techniques Used: Activation Assay, Western Blot, Control, Quantitative RT-PCR, Staining



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    tgfβ signaling phospho-specific antibody microarray  (Full Moon BioSystems)
    90
    Full Moon BioSystems tgfβ signaling phospho-specific antibody microarray
    Altered <t>TGFβ</t> signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.
    Tgfβ Signaling Phospho Specific Antibody Microarray, supplied by Full Moon BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tgfβ signaling phospho-specific antibody microarray/product/Full Moon BioSystems
    Average 90 stars, based on 1 article reviews
    tgfβ signaling phospho-specific antibody microarray - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Altered TGFβ signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.

    Journal: The Journal of Biological Chemistry

    Article Title: Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects * ♦

    doi: 10.1074/jbc.M113.493551

    Figure Lengend Snippet: Altered TGFβ signaling pathway in the tongue of Tgfbr2fl/fl;Wnt1-Cre mice. A, the table lists phosphorylated proteins altered in Tgfbr2fl/fl;Wnt1-Cre tongue as compared with controls expressed as a ratio of phosphorylated protein over nonphosphorylated protein (P/N). Ab, antibody. B, immunoblotting analysis of ABL1 and PKC and their phosphorylated forms (P) in the tongues of E14.5 control (WT; lane 1) and Tgfbr2fl/fl;Wnt1-Cre (CKO; lane 2) mice. C, immunoblotting analysis of the indicated molecules in primary mouse tongue mesenchymal cells from E14.5 control (WT) and Tgfbr2fl/fl;Wnt1-Cre (CKO) mice after treatment with TGFβ1 for 0, 10, 30, and 60 min.

    Article Snippet: The TGFβ signaling phospho-specific antibody microarray, which was designed and manufactured by Full Moon Biosystems, Inc. (Sunnyvale, CA), contains 176 highly specific and well characterized phosphorylation antibodies.

    Techniques: Western Blot, Control

    Ectopic activation of noncanonical TGFβ signaling is prevented by reduction of TβRI/ALK5 in Tgfbr2fl/fl;Wnt1-Cre mice. A and B, immunoblotting analysis of ABL1, phosphorylated (P) ABL1, and tenascin C in tongues from E14.5 control (lane 1), Tgfbr2fl/fl;Wnt1-Cre (lane 2), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (lane 3) mice. C, quantitative RT-PCR analyses of tenascin C (TnC) in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001. D, Gomori's aldehyde fuchsin staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Purple, elastic fibers; green, collagen fibers and nuclei; red, muscle. Scale bar, 500 μm. E, AZAN staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Blue, collagen fibers; red, muscle; orange, nuclei. Bar, 500 μm. F, quantitative RT-PCR analyses of the indicated molecules in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001, *, p < 0.05.

    Journal: The Journal of Biological Chemistry

    Article Title: Noncanonical Transforming Growth Factor β (TGFβ) Signaling in Cranial Neural Crest Cells Causes Tongue Muscle Developmental Defects * ♦

    doi: 10.1074/jbc.M113.493551

    Figure Lengend Snippet: Ectopic activation of noncanonical TGFβ signaling is prevented by reduction of TβRI/ALK5 in Tgfbr2fl/fl;Wnt1-Cre mice. A and B, immunoblotting analysis of ABL1, phosphorylated (P) ABL1, and tenascin C in tongues from E14.5 control (lane 1), Tgfbr2fl/fl;Wnt1-Cre (lane 2), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (lane 3) mice. C, quantitative RT-PCR analyses of tenascin C (TnC) in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001. D, Gomori's aldehyde fuchsin staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Purple, elastic fibers; green, collagen fibers and nuclei; red, muscle. Scale bar, 500 μm. E, AZAN staining in the tongue of Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ mice at E18.5. Blue, collagen fibers; red, muscle; orange, nuclei. Bar, 500 μm. F, quantitative RT-PCR analyses of the indicated molecules in E14.5 tongues of Tgfbr2fl/fl control (blue bars), Tgfbr2fl/fl;Wnt1-Cre (red bars), and Tgfbr2fl/fl;Wnt1-Cre;Alk5fl/+ (green bars) mice. ***, p < 0.001, *, p < 0.05.

    Article Snippet: The TGFβ signaling phospho-specific antibody microarray, which was designed and manufactured by Full Moon Biosystems, Inc. (Sunnyvale, CA), contains 176 highly specific and well characterized phosphorylation antibodies.

    Techniques: Activation Assay, Western Blot, Control, Quantitative RT-PCR, Staining